Quinoline-based tetrazolium prochelators: formazan release, iron sequestration, and antiproliferative efficacy in cancer cells-Reference-Cited by-同舟云学术

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Quinoline-based tetrazolium prochelators: formazan release, iron sequestration, and antiproliferative efficacy in cancer cells

Published:2024 Issue:48 Volume:60 Page:6150-6153
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Sung Yu-Shien¹,Tomat Elisa¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, The University of Arizona, Tucson, AZ 85721-0041, USA

Abstract

Quinoline-based tetrazolium cations undergo intracellular reduction/activation to release formazan chelators, which cause iron deprivation and apoptosis at submicromolar concentrations in cancer cells.

Funder

National Institutes of Health

Division of Chemistry

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC01523A

Reference28 articles.

1. Iron and Cancer: 2020 Vision

2. The Iron Curtain: Macrophages at the Interface of Systemic and Microenvironmental Iron Metabolism and Immune Response in Cancer

3. Persister cancer cells: Iron addiction and vulnerability to ferroptosis

4. Targeting ferroptosis as a vulnerability in cancer

5. Targeting iron to contrast cancer progression

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Catalytic asymmetric Friedländer condensation to construct cyclobutanone-fused quinolines with a quaternary stereogenic centre;Organic Chemistry Frontiers;2024

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