Targeted protein degradation directly engaging lysosomes or proteasomes-Reference-Cited by-同舟云学术

Targeted protein degradation directly engaging lysosomes or proteasomes

Published:2024 Issue:7 Volume:53 Page:3253-3272
ISSN:0306-0012
Container-title:Chemical Society Reviews
language:en
Short-container-title:Chem. Soc. Rev.

Author:

Kim Jiseong¹²^ORCID,Byun Insuk¹²^ORCID,Kim Do Young³^ORCID,Joh Hyunhi³^ORCID,Kim Hak Joong³^ORCID,Lee Min Jae¹²⁴^ORCID

Affiliation:

1. Department of Biochemistry & Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea

2. Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea

3. Department of Chemistry, College of Science, Korea University, Seoul 02841, Korea

4. Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA

Abstract

This review delineates emerging technologies for targeted protein degradation that directly involve lysosomes or proteasomes. It explores their unique features, advantages, and limitations, offering perspectives on future therapeutic applications.

Funder

Samsung

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CS/D3CS00344B

Reference169 articles.

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