Additive-free synthesis of fused tricyclic cyanoisoxazolidines using <i>in situ</i> formed cyanonitrones-Reference-Cited by-同舟云学术

Additive-free synthesis of fused tricyclic cyanoisoxazolidines using in situ formed cyanonitrones

Published:2023 Issue:4 Volume:59 Page:446-449
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Jamali Muhammad Fahad¹²,Yadav Usha¹²,Babu Mary Merlin Manjaly¹,Kant Ruchir³,Mohanan Kishor¹²^ORCID

Affiliation:

1. Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, 226031, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India

3. Molecular and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow, 226031, India

Abstract

Herein, we disclose the generation of cyanonitrone from diazoacetonitrile and nitrosoarene, and its subsequent [3+2] cycloaddition with oxabicyclic alkenes to access an important class of fused tricyclic cyanoisoxazolidines.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D2CC05831F

Reference39 articles.

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2. Total synthesis of securinega alkaloids (−)-norsecurinine, (−)-niruroidine and (−)-flueggine A

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