Affiliation:
1. Medicinal and Process Chemistry Division CSIR-Central Drug Research Institute Lucknow 226031 India
2. Academy of Scientific and Innovative Research Ghaziabad 201002 India
Abstract
AbstractAn additive‐free three‐component reaction of allenamides with in situ generated trifluoromethylnitrones has been uncovered. The reaction afforded an interesting class of trifluoromethylated methyleneisoxazolidines under mild conditions. Additionally, a gram‐scale reaction and the reductive transformation of trifluoromethylated isoxazolidines to aminomethylated allyl alcohol illustrate the high synthetic utility of the present synthetic strategy.
Cited by
1 articles.
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