Stabilisation of metastable polymorphs: the case of paracetamol form III-Reference-Cited by-同舟云学术

Stabilisation of metastable polymorphs: the case of paracetamol form III

Published:2016 Issue:81 Volume:52 Page:12028-12031
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Telford Richard¹²³⁴,Seaton Colin C.¹²³⁴,Clout Alexander⁵⁶⁷⁴,Buanz Asma⁵⁶⁷⁴,Gaisford Simon⁵⁶⁷⁴,Williams Gareth R.⁵⁶⁷⁴^ORCID,Prior Timothy J.⁸⁹¹⁰⁴,Okoye Chidera H.¹¹¹²¹³⁴,Munshi Tasnim¹¹¹²¹³⁴,Scowen Ian J.¹¹¹²¹³⁴

Affiliation:

1. School of Chemistry and Forensic Sciences

2. University of Bradford

3. Bradford

4. UK

5. UCL School of Pharmacy

6. University College London

7. London WC1N 1AX

8. Department of Chemistry

9. University of Hull

10. Hull

11. School of Chemistry

12. University of Lincoln

13. Lincoln LN6 7DL

Abstract

A unique approach is applied in preparing the first ‘air-stable’ formulation of form III of paracetamol, long regarded as a highly unstable form.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC05006A

Reference32 articles.

1. Polymorph control: past, present and future

2. Polymorphism in Processes of Crystallization in Solution: A Practical Review

3. Physicochemical Characterization of the Orthorhombic Polymorph of Paracetamol Crystallized from Solution

4. Crystal structure determination of the elusive paracetamol Form III

5. Preparation and physical characterization of forms II and III of paracetamol

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