Mechanism of INSR clustering with insulin activation and resistance revealed by super-resolution imaging-Reference-Cited by-同舟云学术

Mechanism of INSR clustering with insulin activation and resistance revealed by super-resolution imaging

Published:2022 Issue:20 Volume:14 Page:7747-7755
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Li Hongru¹²,Zhang Jinrui¹,Shi Yan¹,Zhao Guanfang¹²,Xu Haijiao¹,Cai Mingjun¹²^ORCID,Gao Jing¹^ORCID,Wang Hongda¹²³^ORCID

Affiliation:

1. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, P. R. China

2. University of Science and Technology of China, Hefei, Anhui, 230026, P. R. China

3. Laboratory for Marine Biology and Biotechnology, Qing dao National Laboratory for Marine Science and Technology, Wenhai Road, Aoshanwei, Jimo, Qingdao, Shandong 266237, China

Abstract

Insulin receptor functional stability is regulated by βII-spectrin, which plays an important role in insulin regulation of GLUT4 for glucose transport.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Qingdao National Laboratory for Marine Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NR/D2NR01051H

Reference44 articles.

1. The insulin receptor: structure, function, and signaling