An approach towards the synthesis of novel fused nitrogen tricyclic heterocyclic scaffolds via GBB reaction
Author:
Affiliation:
1. Department of Image Science and Engineering
2. Pukyong National University
3. Busan 608-737
4. Republic of Korea
Abstract
A concise and efficient one-pot synthesis of novel N-fused tricyclic derivatives has been developed by using the Groebke–Blackburn–Bienaymé (GBB) reaction, which involved the reaction of 3-amino-1H-indazoles, aldehydes and isonitriles to afford 2-aryl-5H-imidazo[1,2-b]indazol-3-amine derivatives via a formal [4 + 1] cycloaddition reaction.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB02933K
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