Aromatic interactions with heterocycles in water-Reference-Cited by-同舟云学术

Aromatic interactions with heterocycles in water

Published:2023 Issue:40 Volume:14 Page:11131-11140
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Tobajas-Curiel Gloria¹^ORCID,Sun Qingqing²³,Sanders Jeremy K. M.¹^ORCID,Ballester Pablo²⁴^ORCID,Hunter Christopher A.¹^ORCID

Affiliation:

1. Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK

2. Institute of Chemical Research of Catalonia (ICIQ), Barcelona Institute of Science and Technology (BIST), Av. Països Catalans, 16, 43007, Tarragona, Spain

3. Yangzhou University, School of Chemistry and Chemical Engineering, Yangzhou, 225002 Jiangsu, China

4. ICREA, Passeig Lluís Companys 23, 08010 Barcelona, Spain

Abstract

Measurements using chemical double mutant cycles show that non-covalent interactions between heterocyclic and aromatic rings are more favourable in water than chloroform, provided polar sites are solvated by H-bonded water molecules in the complex.

Funder

Ministerio de Ciencia e Innovación

Agencia Estatal de Investigación

Federación Española de Enfermedades Raras

Centres de Recerca de Catalunya

Generalitat de Catalunya

Agència de Gestió d'Ajuts Universitaris i de Recerca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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