A highly selective near infrared fluorescent probe for carboxylesterase 2 and its biological applications-Reference-Cited by-同舟云学术

A highly selective near infrared fluorescent probe for carboxylesterase 2 and its biological applications

Published:2021 Issue:10 Volume:9 Page:2457-2461
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Zhang Xin-Yue¹²³⁴⁵,Liu Tian-Tian⁶⁷⁸⁹¹⁰,Liang Jia-Hao⁶⁷⁸⁹¹⁰,Tian Xiang-Ge¹²³⁴⁵^ORCID,Zhang Bao-Jing⁶⁷⁸⁹¹⁰,Huang Hui-Lian¹²³⁴⁵,Ma Xiao-Chi¹²³⁴⁵^ORCID,Feng Lei⁶⁷⁸⁹¹⁰^ORCID,Sun Cheng-Peng⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Laboratory of Modern Preparation of Traditional Chinese Medicine

2. Ministry of Education

3. Jiangxi University of Traditional Chinese Medicine

4. Nanchang

5. People's Republic of China

6. Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention

7. College of Pharmacy

8. College of Integrative Medicine

9. Dalian Medical University

10. Dalian

Abstract

Carboxylesterase 2 (CES 2) is a key enzyme in the activation of the prodrug irinotecan (CPT-11) in the treatment against colorectal cancer and also has some relationship with the side effect of CPT-11 in clinical applications.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Liaoning Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D0TB02673E

Reference40 articles.

1. Human Carboxylesterase Isozymes: Catalytic Properties and Rational Drug Design

2. Flavonoids as human carboxylesterase 2 inhibitors: Inhibition potentials and molecular docking simulations