Rutin attenuates d-galactose-induced oxidative stress in rats’ brain and liver: molecular docking and experimental approaches

Author:

Saafan Shaimaa M.1,Mohamed Shymaa A.2,Noreldin Ahmed E.3,El Tedawy Fayza A.1,Elewa Yaser H. A.45,Fadly Reda S.1,Al Jaouni Soad Khalil6ORCID,El-Far Ali H.7ORCID,Alsenosy Abdelwahab A.7ORCID

Affiliation:

1. Department of Biochemistry, Animal Health Research Institute (AHRI), Damanhour Branch, Agriculture Research Centre (ARC), Damanhour 22511, Egypt

2. Molecular Biology, Molecular Biology Unit, Medical Technology Centre, Medical Research Institute, Alexandria University, Egypt

3. Department of Histology and Cytology, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, Egypt

4. Department of Histology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt

5. Laboratory of Anatomy, Faculty of Veterinary Medicine, Basic Veterinary Sciences, Hokkaido University, Sapporo 060-0818, Japan

6. Department of Hematology/Pediatric Oncology, Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia

7. Department of Biochemistry, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, Egypt

Abstract

Oxidative stress results from the imbalance between reactive oxygen species (ROS) production and antioxidant defence and is primarily involved in aging.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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