Synthesis and biological evaluation of imidazo[1,5-a]pyridine-benzimidazole hybrids as inhibitors of both tubulin polymerization and PI3K/Akt pathway
Author:
Affiliation:
1. Medicinal Chemistry & Pharmacology
2. CSIR-Indian Institute of Chemical Technology
3. Hyderabad 500 007, India
4. Department of Medicinal Chemistry
5. National Institute of Pharmaceutical Education and Research (NIPER)
6. Hyderabad-500 037, India
Abstract
Imidazo[1,5-a]pyridine-benzimidazole hybrids are firstly reported herein to induce cytotoxicity by targeting microtubules.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB01930J
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