N,O-Benzamide difluoroboron complexes as near-infrared probes for the detection of β-amyloid and tau fibrils

Author:

Chen Yimin12345,Yuan Chang12345,Xie Tianxin12345,Li Yuying12345,Dai Bin678910ORCID,Zhou Kaixiang12345,Liang Yi678910,Dai Jiapei11121310ORCID,Tan Hongwei12345ORCID,Cui Mengchao12345ORCID

Affiliation:

1. Key Laboratory of Radiopharmaceuticals, Ministry of Education

2. College of Chemistry

3. Beijing Normal University

4. Beijing 100875

5. P. R. China

6. State Key Laboratory of Virology

7. College of Life Sciences

8. Wuhan University

9. Wuhan 430072

10. People's Republic of China

11. Wuhan Institute for Neuroscience and Neuroengineering

12. South-Central University for Nationalities

13. Wuhan 430074

Abstract

In this study, a series of organo difluoroboron probes with a BF2 benzamide moiety was designed, prepared and evaluated as Aβ and Tau probes.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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