Bifunctional tetrazole–carboxylate ligand based Zn(ii) complexes: synthesis and their excellent potential anticancer properties

Author:

Tan Li-Tao1,Shen Ting-Xiao1,Jiang Jing-Yi2,Zhong Yu-Jie1,Lin Fang-Qi2,Xue Hong2,Yao Yu-Xin1,Jiang Xin3,Shen Lei1ORCID,He Xin4

Affiliation:

1. Jiangsu Laboratory of Advanced Functional Materials, College of Material Engineering, Changshu Institute of Technology, Changshu, 215500, P. R. China

2. School of Pharmacy, Guilin Medical University, Guilin 541004, Guangxi, P. R. China

3. Affiliated Hospital of Guilin Medical University, Guilin 541000, Guangxi, P. R. China

4. Department of Chemistry and Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology (SUSTech), Shenzhen 518055, P. R. China

Abstract

Two Zn(ii) complexes based on tetrazol were prepared. Nanoparticles of the complexes can inhibit the proliferation of cancer cells in vitro. This work provided a strategy on designing anticancer materials based on coordination complexes.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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