Responses of the gut microbiota and metabolite profiles to sulfated polysaccharides from sea cucumber in humanized microbiota mice

Author:

Liu Zhengqi123,Yan Chunhong12ORCID,Lin Xinping12,Ai Chunqing12ORCID,Dong Xiuping12,Shao Li12,Wang Songtao4,Song Shuang12ORCID,Zhu Beiwei123ORCID

Affiliation:

1. National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, 116034, P. R. China

2. National & Local Joint Engineering Laboratory for Marine Bioactive Polysaccharide Development and Application, Dalian Polytechnic University, Dalian, 116034, P. R. China

3. Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, 100083, P. R. China

4. Luzhou Pinchuang Technology Company Limited, Luzhou, Sichuan 646000, P. R. China

Abstract

Sea cucumber sulfated polysaccharides (SCSPsj) enhance the relative abundance of Lactobacillus by promoting biofilm formation and mucus binding, and further regulate the metabolism in a humanized microbiota mice model.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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