Efficient full-length IgG secretion and sorting from single yeast clones in droplet picoreactors-Reference-Cited by-同舟云学术

Efficient full-length IgG secretion and sorting from single yeast clones in droplet picoreactors

Published:2023 Issue:15 Volume:23 Page:3487-3500
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Lebrun Esteban¹²^ORCID,Shenshin Vasily¹^ORCID,Plaire Cécile¹^ORCID,Vigneres Vincent³,Pizette Théo¹,Dumas Bruno¹,Nicaud Jean-Marc²^ORCID,Mottet Guillaume¹^ORCID

Affiliation:

1. Large Molecules Research, Sanofi, 94400 Vitry-Sur-Seine, France

2. Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350 Jouy-en-Josas, France

3. Arcale, 31100 Toulouse, France

Abstract

We present a novel antibody screening platform based on antibody-secreting yeast cells encapsulated in droplets. This platform provides an antibody discovery process capable of screening large antibody libraries in their final soluble IgG format.

Funder

Association Nationale de la Recherche et de la Technologie

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D3LC00403A

Reference63 articles.

1. The therapeutic monoclonal antibody market

2. The Increasingly Human and Profitable Monoclonal Antibody Market

3. Antibodies to watch in 2020

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