Targeted delivery of a guanidine-pendant Pt(iv)-backboned poly-prodrug by an anisamide-functionalized polypeptide-Reference-Cited by-同舟云学术

Targeted delivery of a guanidine-pendant Pt(iv)-backboned poly-prodrug by an anisamide-functionalized polypeptide

Published:2017 Issue:48 Volume:5 Page:9546-9557
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Li Shao-Lu¹²³⁴⁵^ORCID,Wang Yaoyi⁶⁷⁸⁹¹⁰^ORCID,Zhang Jingfang⁶⁷⁸⁹¹⁰^ORCID,Wei Wei¹¹¹²¹³¹⁴⁵,Lu Hua⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. State Key Laboratory of Separation Membranes and Membrane Processes

2. School of Materials Science and Engineering

3. Tianjin Polytechnic University

4. Tianjin 300387

5. People's Republic of China

6. Beijing National Laboratory for Molecular Sciences

7. Center for Soft Matter Science and Engineering

8. Key Laboratory of Polymer Chemistry and Physics of Ministry of Education

9. College of Chemistry and Molecular Engineering

10. Peking University

11. State Key Laboratory of Biochemical Engineering

12. Institute of Process Engineering

13. Chinese Academy of Sciences

14. Beijing

Abstract

A guanidine-pendant Pt(iv)-backboned prodrug-like polymer was synthesized and formulated with an anisamide-functionalized polypeptide for targeted delivery and enhanced cellular uptake.

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C7TB02513K

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