Whey protein and soy protein prevent obesity by upregulating uncoupling protein 1 to activate brown adipose tissue and promote white adipose tissue browning in high-fat diet-fed mice

Author:

Ji Andong1ORCID,Chen Wei2,Zhang Tianyu1ORCID,Shi Runjia1,Wang Xinqi1,Wang Yan1,Xu Huina1,Li Duo134ORCID

Affiliation:

1. Institute of Nutrition and Health, School of Public Health, Qingdao University, Qingdao 266071, China

2. Department of Clinical Nutrition, Chinese Academy of Medical Sciences-Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

3. Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, China

4. Department of Nutrition, Dietetics and Food, Monash University, Melbourne, VIC 3168, Australia

Abstract

Whey protein is more effective than soy protein in preventing obesity in mice, probably by suppressing lipogenesis in adipose tissues, activating BAT and promoting the browning of iWAT.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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