Design of novel potential aromatase inhibitors via hybrid pharmacophore approach: docking improvement using the QM/MM method
Author:
Affiliation:
1. Department of Medicinal Chemistry
2. School of Pharmacy and Pharmaceutical Sciences
3. Isfahan University of Medical Sciences
4. Isfahan
5. I. R. Iran
6. Department of Chemistry
7. Isfahan University of Technology
Abstract
QM/MM and docking methods were used for designing novel hybrid aromatase inhibitors incorporating benzofuran, imidazole and quinazolinone moieties.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA10097F
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