Facile access to C-substituted piperazin-2-ones and mianserin derivative enabled by chemoselective carbene insertion and cyclization cascade
Author:
Affiliation:
1. Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India
2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India
Abstract
Funder
Science and Engineering Research Board
University Grants Commission
Publisher
Royal Society of Chemistry (RSC)
Link
http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC00959B
Reference41 articles.
1. Synthesis and Pharmacological Testing of 1,2,3,4,10,14b-Hexahydro-6-methoxy-2-methyldibenzo[c,f]pyrazino[1,2-a]azepin and Its Enantiomers in Comparison with the Two Antidepressants Mianserin and Mirtazapine
2. MCR Synthesis of Praziquantel Derivatives
3. Discovery of a Novel Class of Potent HCV NS4B Inhibitors: SAR Studies on Piperazinone Derivatives
4. Bioactive heterocycles containing endocyclic N-hydroxy groups
5. Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide−Epoxide Cyclization
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