Synthesis and Pharmacological Testing of 1,2,3,4,10,14b-Hexahydro-6-methoxy-2-methyldibenzo[c,f]pyrazino[1,2-a]azepin and Its Enantiomers in Comparison with the Two Antidepressants Mianserin and Mirtazapine-Reference-Cited by-同舟云学术

Synthesis and Pharmacological Testing of 1,2,3,4,10,14b-Hexahydro-6-methoxy-2-methyldibenzo[c,f]pyrazino[1,2-a]azepin and Its Enantiomers in Comparison with the Two Antidepressants Mianserin and Mirtazapine

Published:2002-06-19 Issue:15 Volume:45 Page:3280-3285
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wikström Håkan V.¹,Mensonides-Harsema Marguérite M.¹,Cremers Thomas I. F. H.¹,Moltzen Ejner K.¹,Arnt Jørn¹

Affiliation:

1. Department of Medicinal Chemistry, University Center for Pharmacy, University of Groningen, A. Deusinglaan 1, NL-9713 AV, Groningen, The Netherlands, and Department of Medicinal Chemistry and Pharmacology, H. Lundbeck A.S., Copenhagen, Denmark

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm010566d

Reference33 articles.

1. THE CATECHOLAMINE HYPOTHESIS OF AFFECTIVE DISORDERS: A REVIEW OF SUPPORTING EVIDENCE

2. Differential Effect of Gepirone on Presynaptic and Postsynaptic Serotonin Receptors

3. The α2-adrenoceptor antagonist Org 3770 enhances serotonin transmission in vivo

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