Autophagy is an important action mode for functionalized selenium nanoparticles to exhibit anti-colorectal cancer activity
Author:
Affiliation:
1. The First Affiliated Hospital
2. and Department of Chemistry
3. Jinan University
4. Guangzhou 510632
5. China
6. Department of Applied Biology and Chemical Technology
7. The Hong Kong Polytechnic University
8. Hong Kong
Abstract
This study demonstrates the high efficacy of PTR-SeNPs for therapy of colorectal cancer and reveals the important role of autophagy in promoting apoptosis and cell cycle arrest to induce cell death.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Guangdong Province
China Postdoctoral Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2018/BM/C8BM00670A
Reference41 articles.
1. Endocytosis at the nanoscale
2. ARF, autophagy and tumor suppression
3. Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance
4. Novel monofunctional platinum (II) complex Mono-Pt induces apoptosis-independent autophagic cell death in human ovarian carcinoma cells, distinct from cisplatin
5. Induction of apoptosis and autophagy by sodium selenite in A549 human lung carcinoma cells through generation of reactive oxygen species
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