Copper complexes as prospective anticancer agents: in vitro and in vivo evaluation, selective targeting of cancer cells by DNA damage and S phase arrest-Reference-Cited by-同舟云学术

Copper complexes as prospective anticancer agents: in vitro and in vivo evaluation, selective targeting of cancer cells by DNA damage and S phase arrest

Published:2018 Issue:30 Volume:8 Page:16973-16990
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mahendiran Dharmasivam¹²³⁴,Amuthakala Sethu¹²³⁴,Bhuvanesh Nattamai S. P.⁵⁶⁷⁸,Kumar Raju Senthil⁹¹⁰¹¹⁴,Rahiman Aziz Kalilur¹²³⁴^ORCID

Affiliation:

1. Post-Graduate and Research Department of Chemistry

2. The New College (Autonomous)

3. Chennai 600 014

4. India

5. Department of Chemistry

6. Texas A & M University

7. College Station

8. USA

9. Department of Pharmaceutical Chemistry

10. Swamy Vivekanandha College of Pharmacy

11. Tiruchengodu 637 205

Abstract

The thiosemicarbazone-based copper(i) complexes causing S phase arrest and apoptosis involving the mitochondrial controlled pathway has been investigated.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA00954F

Reference65 articles.

1. A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics

2. Zinc(II)–Thiosemicarbazone Complexes Are Localized to the Lysosomal Compartment Where They Transmetallate with Copper Ions to Induce Cytotoxicity

3. http://www.clinicaltrials.gov

4. Cu–ATSM: A radiopharmaceutical for the PET imaging of hypoxia

5. Increasing Cu bioavailability inhibits A oligomers and tau phosphorylation

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