Zinc(II)–Thiosemicarbazone Complexes Are Localized to the Lysosomal Compartment Where They Transmetallate with Copper Ions to Induce Cytotoxicity-Reference-Cited by-同舟云学术

Zinc(II)–Thiosemicarbazone Complexes Are Localized to the Lysosomal Compartment Where They Transmetallate with Copper Ions to Induce Cytotoxicity

Published:2016-04-26 Issue:10 Volume:59 Page:4965-4984
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Stacy Alexandra E.¹,Palanimuthu Duraippandi¹,Bernhardt Paul V.²,Kalinowski Danuta S.¹,Jansson Patric J.¹,Richardson Des R.¹

Affiliation:

1. Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, The University of Sydney, Blackburn Building (D06), Level 5, Sydney, New South Wales 2006, Australia

2. School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia

Funder

National Health and Medical Research Council

Cancer Institute NSW

Australian Research Council

Sydney Medical School

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00238

Reference91 articles.

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3. Antifungal and antitumor activity of heterocyclic thiosemicarbazones and their metal complexes: current status

4. 2-Acetylpyridine thiosemicarbazones. 1. A new class of potential antimalarial agents

5. Activity of p-Aminobenzaldehyde, 3-Thiosemicarbazone on Vaccinia Virus in the Chick Embryo and in the Mouse

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