Quantitation of the Fe spatial distribution in biological tissue by online double isotope dilution analysis with LA-ICP-MS: a strategy for estimating measurement uncertainty
Author:
Affiliation:
1. Inorganic Analysis, Science and Innovation
2. LGC Group
3. Teddington
4. UK
5. ESI New Wave Research Division
6. Bozeman
7. USA
8. Chemistry Department
9. School of Science
10. Loughborough University
11. Loughborough
Abstract
A strategy, systematically developed, is reported for the quantitative analysis of the Fe spatial distribution in biological tissue using laser ablation with ICP-MS and on-line double isotope dilution analysis.
Funder
Innovate UK
Publisher
Royal Society of Chemistry (RSC)
Subject
Spectroscopy,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/JA/C5JA00351B
Reference37 articles.
1. Imaging of essential and toxic elements in biological tissues by LA-ICP-MS
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3. Bioimaging of metals by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)
4. Imaging and spatial distribution of β-amyloid peptide and metal ions in Alzheimer’s plaques by laser ablation–inductively coupled plasma–mass spectrometry
5. Iron genes, iron load and risk of Alzheimer's disease
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