A synthetic transcription factor pair mimic for precise recruitment of an epigenetic modifier to the targeted DNA locus-Reference-Cited by-同舟云学术

A synthetic transcription factor pair mimic for precise recruitment of an epigenetic modifier to the targeted DNA locus

Published:2020 Issue:15 Volume:56 Page:2296-2299
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Yu Zutao¹²³⁴⁵,Ai Mengting¹²³⁴,Samanta Soumen K.⁶⁷⁸⁹,Hashiya Fumitaka¹²³⁴,Taniguchi Junichi¹²³⁴,Asamitsu Sefan¹²³⁴,Ikeda Shuji¹²³⁴,Hashiya Kaori¹²³⁴,Bando Toshikazu¹²³⁴,Pandian Ganesh N.⁵³¹⁰⁴,Isaacs Lyle⁶⁷⁸⁹^ORCID,Sugiyama Hiroshi¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Graduate School of Science

3. Kyoto University

4. Japan

5. Institute for Integrated Cell-Material Sciences (iCeMS)

6. Department of Chemistry and Biochemistry

7. University of Maryland

8. Maryland 20742

9. USA

10. Kyoto 606-8502

Abstract

ePIP–HoGu not only mimics the transcription factor operation as pairs but is also capable of recruiting the epigenetic modifiers to a particular DNA locus.

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/C9CC09608F

Reference34 articles.

1. DNA-dependent formation of transcription factor pairs alters their binding specificity

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4. Stimuli-responsive selection of target DNA sequences by synthetic bZIP peptides

5. Sequence-Specific DNA Binding by Noncovalent Peptide–Tripyrrole Conjugates

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