Dihydroisoquinoline copper(ii) complexes: crystal structures, cytotoxicity, and action mechanism-Reference-Cited by-同舟云学术

Dihydroisoquinoline copper(ii) complexes: crystal structures, cytotoxicity, and action mechanism

Published:2015 Issue:99 Volume:5 Page:81313-81323
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Huang Ke-Bin¹²³⁴⁵,Chen Zhen-Feng¹²³⁴,Liu Yan-Cheng¹²³⁴^ORCID,Xie Xiao-Li¹²³⁴,Liang Hong¹²³⁴⁵

Affiliation:

1. Guangxi Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources

2. School of Chemistry and Pharmacy of Guangxi Normal University

3. Guilin 541004

4. P. R. China

5. School of Chemistry of Nankai University

Abstract

Three new copper(ii) complexes with dihydroisoquinoline were synthesized. They exhibited considerable cytotoxicity, achieved through the induction of cell apoptosisviathe intrinsic pathways of caspase–mitochondria.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA15789G

Reference51 articles.

1. Direct Cellular Responses to Platinum-Induced DNA Damage

2. In Vitro Anticancer Activity of cis-Diammineplatinum(II) Complexes with β-Diketonate Leaving Group Ligands

3. What do we know about the reduction of Pt(IV) pro-drugs?

4. Nuclear Permeable Ruthenium(II) β-Carboline Complexes Induce Autophagy To Antagonize Mitochondrial-Mediated Apoptosis

5. Role of Metalation in the Topoisomerase IIα Inhibition and Antiproliferation Activity of a Series of α-Heterocyclic-N4-Substituted Thiosemicarbazones and Their Cu(II) Complexes

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