Nanoscopic insights into the surface conformation of neurotoxic amyloid β oligomers

Author:

Banchelli Martina1234,Cascella Roberta5674ORCID,D'Andrea Cristiano1234ORCID,Cabaj Leszek8910,Osticioli Iacopo1234,Ciofini Daniele1234,Li Mai Suan1112131014ORCID,Skupień Krzysztof8910,de Angelis Marella1234,Siano Salvatore1234,Cecchi Cristina5674ORCID,Pini Roberto1234,La Penna Giovanni15234ORCID,Chiti Fabrizio5674ORCID,Matteini Paolo1234ORCID

Affiliation:

1. Institute of Applied Physics “Nello Carrara”

2. National Research Council

3. I-50019 Sesto Fiorentino

4. Italy

5. Department of Experimental and Clinical Biomedical Sciences

6. University of Florence

7. I-50134 Firenze

8. 3D-Nano

9. 30-702 Kraków

10. Poland

11. Institute of Physics

12. Polish Academy of Sciences

13. 02-668 Warsaw

14. Institute for Computational Science and Technology

15. Institute of Chemistry of Organometallic Compounds

Abstract

Unraveling characteristic structural determinants at the basis of Aβ42 oligomers' neurotoxicity by a sub-molecular SERS investigation of their surface.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Narodowe Centrum Badań i Rozwoju

Regione Toscana

Ministero degli Affari Esteri e della Cooperazione Internazionale

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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