Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease
Author:
Affiliation:
1. Biophysics and Department of Chemistry
2. University of Michigan
3. Ann Arbor, USA
Abstract
The association of the amyloid-β (Aβ) peptide with cellular membranes is hypothesized to be the underlying phenomenon of neurotoxicity in Alzheimer's disease.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/CS/C3CS60431D
Reference55 articles.
1. Alzheimer's Association: Facts & Figures, Alzheimer's & Dementia , 2013, 9
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5. Amyloidogenic Protein-Membrane Interactions: Mechanistic Insight from Model Systems
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