Quantitative nanoscale electrostatics of viruses

Author:

Hernando-Pérez M.123,Cartagena-Rivera A. X.456,Lošdorfer Božič A.7891011,Carrillo P. J. P.123,San Martín C.131415,Mateu M. G.123,Raman A.123,Podgornik R.161711910,de Pablo P. J.123

Affiliation:

1. Departamento de Física de la Materia Condensada and Condensed Matter Physics Center - IFIMAC

2. Universidad Autónoma de Madrid

3. Spain

4. Birck Nanotechnology Center & School of Mechanical Engineering

5. Purdue University

6. , USA

7. Max Planck Institute for Biology of Ageing

8. D-50931 Cologne, Germany

9. Department of Theoretical Physics

10. Jozef Stefan Institute

11. SI-1000 Ljubljana, Slovenia

12. Centro de Biología Molecular Severo Ochoa (Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid)

13. Department of Structure of Macromolecules and Nanobiomedicine Initiative

14. Centro Nacional de Biotecnología/CSIC

15. Cantoblanco, Spain

16. Department of Physics

17. University of Ljubljana

Abstract

The recognition events between viruses and host cells are dominated by both specific and non-specific electrostatic interactions determined by the charge of viral particles. Here we probe the charge of individual viruses in aqueous solutions by measuring the electrostatic force between each viral particle and the Atomic Force Microscope tip.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Reference55 articles.

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