Diastereo- and enantioselective construction of biologically important pyrrolo[1,2-a]indole scaffolds via catalytic asymmetric [3 + 2] cyclodimerizations of 3-alkyl-2-vinylindoles-Reference-Cited by-同舟云学术

Diastereo- and enantioselective construction of biologically important pyrrolo[1,2-a]indole scaffolds via catalytic asymmetric [3 + 2] cyclodimerizations of 3-alkyl-2-vinylindoles

Published:2017 Issue:1 Volume:4 Page:57-68
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhu Zi-Qi¹²³⁴⁵,Yin Lei¹²³⁴⁵,Wang Yang¹²³⁴⁵,Shen Yang¹²³⁴⁵,Li Can¹²³⁴⁵,Mei Guang-Jian¹²³⁴⁵,Shi Feng¹²³⁴⁵

Affiliation:

1. Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials

2. School of Chemistry and Chemical Engineering

3. Jiangsu Normal University

4. Xuzhou

5. China

Abstract

A catalytic asymmetric [3 + 2] cyclodimerization of 3-alkyl-2-vinylindoles has been established, which efficiently constructed a pyrrolo[1,2-a]indole scaffold in a diastereo- and enantioselective fashion.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/QO/C6QO00446F

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1. Mapping the Melatonin Receptor. 6. Melatonin Agonists and Antagonists Derived from 6H-Isoindolo[2,1-a]indoles, 5,6-Dihydroindolo[2,1-a]isoquinolines, and 6,7-Dihydro-5H-benzo[c]azepino[2,1-a]indoles

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3. Identification of prostaglandin D2 receptor antagonists based on a tetrahydropyridoindole scaffold