Lipophilicity-dependent ruthenium N-heterocyclic carbene complexes as potential anticancer agents-Reference-Cited by-同舟云学术

Lipophilicity-dependent ruthenium N-heterocyclic carbene complexes as potential anticancer agents

Published:2015 Issue:16 Volume:44 Page:7324-7331
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Lv Gaochao¹²³⁴⁵,Guo Liubin¹²³⁴⁵,Qiu Ling¹²³⁴⁵,Yang Hui¹²³⁴⁵,Wang Tengfei¹²³⁴⁵,Liu Hong¹²³⁴⁵,Lin Jianguo¹²³⁴⁵

Affiliation:

1. Key Laboratory of Nuclear Medicine

2. Ministry of Health

3. Jiangsu Key Laboratory of Molecular Nuclear Medicine

4. Jiangsu Institute of Nuclear Medicine

5. Wuxi 214063

Abstract

Five novel Ru(ii)–N-heterocyclic carbenes (NHC) were synthesized and biologically evaluated, one of which showed superior activity against PC-3 cell lines and 6 fold more activity than cisplatin.

Funder

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/DT/C5DT00169B

Reference27 articles.

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5. Synthesis, Characterization, and Cytotoxic Activity of Au I N,S‐Heterocyclic Carbenes Derived from Peptides Containing L ‐Thiazolylalanine

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