A three-component reaction of cyclobutanone oxime esters, sulfur dioxide and <i>N</i>-alkyl-<i>N</i>-methacryloyl benzamides-Reference-Cited by-同舟云学术

A three-component reaction of cyclobutanone oxime esters, sulfur dioxide and N-alkyl-N-methacryloyl benzamides

Published:2023 Issue:45 Volume:21 Page:9021-9028
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ye Shengqing¹²³^ORCID,Zhuang Chen⁴,Lv Jiajing²,Zhang Chao²,Chen Qi²,Wu Zhiyuan²,Wu Jie²^ORCID,Xia Hongguang¹³

Affiliation:

1. Department of Biochemistry & Research Center of Clinical Pharmacy of the First Affiliated Hospital, Zhejiang University School of medicine, Hangzhou 310058, China

2. Taizhou Central Hospital (Taizhou University Hospital) & School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 318000, China

3. Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, Hangzhou 311121, China

4. Alberta Institute, Wenzhou Medical University, Wenzhou 325035, China

Abstract

A three-component reaction of cyclobutanone oxime esters, DABCO·(SO2)2 and N-alkyl-N-methacryloyl benzamides was developed for the generation of sulfonyl-containing isoquinoline-1,3-(2H,4H)-diones.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01439H

Reference65 articles.

1. 4-Substituted 2-Hydroxyisoquinoline-1,3(2H,4H)-diones as a Novel Class of HIV-1 Integrase Inhibitors

2. Selenium-containing naphthalimides as anticancer agents: Design, synthesis and bioactivity

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4. Magnesium Chelating 2-Hydroxyisoquinoline-1,3(2H,4H)-diones, as Inhibitors of HIV-1 Integrase and/or the HIV-1 Reverse Transcriptase Ribonuclease H Domain: Discovery of a Novel Selective Inhibitor of the Ribonuclease H Function