A concise/catalytic approach for the construction of the C14–C28 fragment of eribulin-Reference-Cited by-同舟云学术

A concise/catalytic approach for the construction of the C14–C28 fragment of eribulin

Published:2021 Issue:20 Volume:19 Page:4542-4550
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Senapati Sibadatta¹²³⁴⁵,Ramana Chepuri V.¹²³⁴⁵^ORCID

Affiliation:

1. Division of Organic Chemistry

2. National Chemical Laboratory

3. Pune-411008

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

Abstract

A diastereoselective gold cyclisation and a Sharpless asymmetric dihydroxylation–cycloetherification protocol were carried out for the construction of the key disaccharide unit (C14–C28) of eribulin mesylate with a linear sequence of 14 steps.

Funder

Council of Scientific and Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00661D

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