A novel FRET-based fluorescent probe for the selective detection of hydrogen sulfide (H2S) and its application for bioimaging-Reference-Cited by-同舟云学术

A novel FRET-based fluorescent probe for the selective detection of hydrogen sulfide (H2S) and its application for bioimaging

Published:2018 Issue:30 Volume:6 Page:4903-4908
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Zhao Qi¹²³⁴⁵,Huo Fangjun⁶⁴⁵^ORCID,Kang Jin¹²³⁴⁵,Zhang Yongbin¹²³⁴⁵,Yin Caixia¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education

2. Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province

3. Institute of Molecular Science, Shanxi University

4. Taiyuan 030006

5. China

6. Research Institute of Applied Chemistry, Shanxi University

Abstract

Herein, our group developed a fast response fluorescent probe (Flu-N3) for H₂S on the basis of the 7-amino-4-methylcoumarin and fluorescein FRET system with high sensitivity and selectivity and a low detection limit of 0.031 μM. Moreover, the probe was successfully applied to image exogenous and endogenous H₂S in living cells and nude mice.

Funder

National Natural Science Foundation of China

Shanxi Province Science Foundation for Youths

Shanxi University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2018/TB/C8TB01070F

Reference45 articles.

1. Determination of sulfide in brain tissue and rumen fluid by ion-interaction reversed-phase high-performance liquid chromatography