Microwave-assisted synthesis of the anticancer drug cisplatin, cis-[Pt(NH3)2Cl2]

Author:

Petruzzella Emanuele1234,Chirosca Cristian V.1234,Heidenga Cameron S.1234,Hoeschele James D.1234

Affiliation:

1. Department of Chemistry

2. Eastern Michigan University

3. Ypsilanti

4. USA

Abstract

A rapid one-step microwave-assisted synthesis of cisplatin and two purification methods were developed. The process requires about 80 min and could be used to incorporate short-lived Pt radionuclides into cisplatin.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Reference28 articles.

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3. G. L. Powell , in Microwave Heating as a Tool for Sustainable Chemistry, ed. N. A. Leadbeater's, CRC Press, Taylor & Francis, Boca Raton, FL, 2011

4. Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode

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