Hydrogel based lipid-oligonucleotides: a new route to self-delivery of therapeutic sequences-Reference-Cited by-同舟云学术

Hydrogel based lipid-oligonucleotides: a new route to self-delivery of therapeutic sequences

Published:2021 Issue:10 Volume:9 Page:3638-3644
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Benizri Sébastien¹²³^ORCID,Gaubert Alexandra¹²³,Soulard Charlotte¹²³,Gontier Étienne⁴⁵¹⁶⁷,Svahn Isabelle⁴⁵¹⁶⁷,Rocchi Palma⁸⁹¹⁰¹¹¹²,Vacher Gaëlle¹²³,Barthélémy Philippe¹²³^ORCID

Affiliation:

1. University of Bordeaux

2. F-33076 Bordeaux

3. France

4. Bordeaux Imaging Center

5. UMS3420 CNRS

6. US4 INSERM

7. Bordeaux

8. Centre de Recherche en Cancérologie de Marseille

9. CRCM

10. Inserm UMR1068

11. CNRS UMR7258

12. Aix-Marseille University U105

Abstract

Lipid-oligonucleotide conjugates self-assemble to form entangled pearl-necklace networks stabilizing gels. Owing to these properties, the oligonucleotide sequences exhibit a prolonged release after subcutaneous administration.

Funder

Inserm Transfert

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00273B

Reference36 articles.

1. Therapeutic Antisense Oligonucleotides Are Coming of Age

2. Antisense therapy for cancer