Knocking down disease: a progress report on siRNA therapeutics
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg3978.pdf
Reference95 articles.
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2. Stephenson, M. L. & Zamecnik, P. C. Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc. Natl Acad. Sci. USA 75, 285–288 (1978). First demonstration of the possibility of inhibiting gene expression using oligonucleotides.
3. Kole, R., Krainer, A. R. & Altman, S. RNA therapeutics: beyond RNA interference and antisense oligonucleotides. Nat. Rev. Drug Discov. 11, 125–140 (2012).
4. Bennett, C. F. & Swayze, E. E. RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform. Annu. Rev. Pharmacol. Toxicol. 50, 259–293 (2010).
5. Sharma, V. K., Sharma, R. K. & Singh, S. K. Antisense oligonucleotides: modifications and clinical trials. Med. Chem. Commun. 5, 1454–1471 (2014).
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