A modular approach to prepare enantioenriched cyclobutanes: synthesis of (+)-rumphellaone A-Reference-Cited by-同舟云学术

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A modular approach to prepare enantioenriched cyclobutanes: synthesis of (+)-rumphellaone A

Published:2019 Issue:8 Volume:10 Page:2315-2319
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Beck Jordan C.¹²³⁴^ORCID,Lacker Caitlin R.¹²³⁴^ORCID,Chapman Lauren M.¹²³⁴,Reisman Sarah E.¹²³⁴^ORCID

Affiliation:

1. The Warren and Katharine Schlinger Laboratory of Chemistry and Chemical Engineering

2. California Institute of Technology

3. Pasadena

4. USA

Abstract

A modular synthesis of enantioenriched polyfunctionalized cyclobutanes was developed and applied to the synthesis of (+)-rumphellaone A.

Funder

Research Corporation for Science Advancement

National Institute of General Medical Sciences

Division of Chemistry

Division of Graduate Education

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C8SC05444D

Reference57 articles.

1. Bioactive cyclobutane-containing alkaloids

2. How cyclobutanes are assembled in nature – insights from quantum chemistry

3. Cyclobutane Biomolecules: Synthetic Approaches to Amino Acids, Peptides and Nucleosides

4. Psiguadials A and B, Two Novel Meroterpenoids with Unusual Skeletons from the Leaves of Psidium guajava

5. Efficacy and Safety of Mirogabalin (DS-5565) for the Treatment of Diabetic Peripheral Neuropathic Pain: A Randomized, Double-Blind, Placebo- and Active Comparator–Controlled, Adaptive Proof-of-Concept Phase 2 Study

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