Kinetic stability modulation of polymeric nanoparticles for enhanced detection of influenza virus via penetration of viral fusion peptides

Author:

Park Chaewon1,Lim Jong-Woo1,Park Geunseon1,Kim Hyun-Ouk2ORCID,Lee Sojeong1,Kwon Yuri H.1,Kim Seong-Eun3,Yeom Minjoo4,Na Woonsung56ORCID,Song Daesub4,Kim Eunjung7ORCID,Haam Seungjoo1ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 03722, Republic of Korea

2. Division of Chemical Engineering and Bioengineering College of Art, Kangwon National University, Chuncheon 24341, Republic of Korea

3. Huvet Bio Inc, Seoul 05836, Republic of Korea

4. College of Pharmacy, Korea University, Sejong 30019, Republic of Korea

5. College of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of Korea

6. Animal Medical Institute, Chonnam National University, Gwangju 61186, Republic of Korea

7. Division of Bioengineering, Incheon National University, Incheon 22012, Republic of Korea

Abstract

Virus detection is materialized by engineered polymeric nanoparticles as host cell-mimetic decoys and analysis of the kinetic stability of nanoparticles against fusion peptides provides insight into the design of influenza viruses detection system.

Funder

National Research Foundation

Ministry of Environment

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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