Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist-Reference-Cited by-同舟云学术

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Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist

Published:2019 Issue:5 Volume:17 Page:1225-1237
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Compton Benjamin J.¹²³⁴,Farrand Kathryn J.⁵⁶⁴,Tang Ching-wen⁷⁸⁴⁹³,Osmond Taryn L.⁵⁶⁴⁹³,Speir Mary⁵⁶⁴,Authier-Hall Astrid⁵⁶⁴⁷⁸,Wang Jing¹⁰¹¹¹²¹³,Ferguson Peter M.¹⁴⁶⁴^ORCID,Chan Susanna T. S.¹²³⁴,Anderson Regan J.¹²³⁴^ORCID,Cooney Taylor R.¹²³⁴⁷^ORCID,Hayman Colin M.¹²³⁴,Williams Geoffrey M.⁷⁸⁴¹⁵¹⁶,Brimble Margaret A⁷⁸⁴¹⁵¹⁶^ORCID,Brooks Collin R.⁵⁶⁴,Yong Lin-Kin¹⁷¹⁸¹⁹²⁰¹³^ORCID,Metelitsa Leonid S.¹⁷¹⁸¹⁹²⁰¹³,Zajonc Dirk M.¹⁰¹¹¹²¹³²¹,Godfrey Dale I.²²²³²⁴²⁵²⁶,Gasser Olivier⁵⁶⁴,Weinkove Robert⁵⁶⁴¹⁴⁶,Painter Gavin F.¹²³⁴⁹^ORCID,Hermans Ian F.⁵⁶⁴⁷⁸

Affiliation:

1. The Ferrier Research Institute

2. Victoria University of Wellington

3. Lower Hutt

4. New Zealand

5. Malaghan Institute of Medical Research

6. Wellington

7. Maurice Wilkins Centre for Molecular Biodiscovery

8. Auckland

9. Avalia Immunotherapies

10. Division of Immune Regulation

11. La Jolla Institute for Immunology

12. La Jolla

13. USA

14. Capital and Coast District Health Board

15. School of Biological Sciences

16. The University of Auckland

17. Texas Children's Cancer Center

18. Department of Pediatrics

19. Baylor College of Medicine

20. Houston

21. Department of Internal Medicine

22. Department of Microbiology and Immunology

23. at the Doherty Institute for Infection and Immunity

24. The University of Melbourne

25. Melbourne

26. Australia

Abstract

Through chemical synthesis we have designed out the toxicity associated with the powerful vaccine adjuvant α-GalCer.

Funder

Health Research Council of New Zealand

Ministry of Business, Innovation and Employment

Genesis Oncology Trust

National Health and Medical Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB02982B

Reference48 articles.

1. CD1d-dependent endogenous and exogenous lipid antigen presentation

2. CD1d-Restricted and TCR-Mediated Activation of V α 14 NKT Cells by Glycosylceramides

3. Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions

4. Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

5. Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria

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