Deferitazole, a new orally active iron chelator-Reference-Cited by-同舟云学术

Deferitazole, a new orally active iron chelator

Published:2015 Issue:11 Volume:44 Page:5197-5204
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Hider Robert C.¹²³⁴,Kong Xiaole¹²³⁴,Abbate Vincenzo¹²³⁴,Harland Rachel⁵⁶⁴,Conlon Kelly⁵⁶⁴,Luker Tim⁵⁶⁴

Affiliation:

1. Institute of Pharmaceutical Science

2. King's College

3. London

4. UK

5. Shire Pharmaceutical Development Ltd

6. Basingstoke

Abstract

Deferitazole possesses a high affinity and selectivity for iron(iii), forming an equilibrium mixture of two Fe^III(deferitazole)₂complexes, under biological conditions.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/DT/C5DT00063G

Reference44 articles.

1. R. Crichton , Iron Metabolism, Wiley, Chichester, 3rd edn, 2009

2. Disorders of Iron Metabolism

3. J. C. Barton and C. Q.Edwards, Hemochromatosis Genetics, Pathophysiology, Diagnosis and Treatment, Cambridge University Press, Cambridge, UK, 2000

4. Current issues with blood transfusions in sickle cell disease

5. Mechanism of Iron Toxicity

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The diversity and utility of arylthiazoline and aryloxazoline siderophores: Challenges of coordination chemistry, biological activity and selected applications;Coordination Chemistry Reviews;2024-02

2. Salvage Structures, Known as Iron Chelating Agents, Acquired from the Nature and Matured in the Labs;CURR MED CHEM;2024

3. Exploration of the novel phthalimide-hydroxypyridinone derivatives as multifunctional drug candidates against Alzheimer’s disease;Bioorganic Chemistry;2023-12

4. Understanding the Intricacies of Iron Overload Associated with β-Thalassemia: A Comprehensive Review;Thalassemia Reports;2023-07-03

5. Regio- and stereoselective syntheses of chiral α-quaternary (Z)-trisubstituted allylic amino acidsviasynergistic Pd/Cu catalysis;Chemical Communications;2023