Dual-color control of nucleotide polymerization sensed by a fluorescence actuator
Author:
Affiliation:
1. CIGMH
2. Departamento Ciências da Vida
3. Faculdade de Ciências e Tecnologia
4. Universidade Nova de Lisboa
5. Campus de Caparica
6. REQUIMTE
7. Departamento de Química
Abstract
Spatial and temporal control of molecular mechanisms can be achieved using photolabile bonds that connect biomolecules to protective caging groups, which can be cleaved upon irradiation of a specific wavelength, releasing the biomolecule ready-to-use.
Publisher
Springer Science and Business Media LLC
Subject
Physical and Theoretical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/PP/C3PP50438G
Reference16 articles.
1. Photochemical tools to study dynamic biological processes
2. Chemistry and biological applications of photo-labile organic molecules
3. Principles and Applications of the Photochemical Control of Cellular Processes
4. Illuminating the Chemistry of Life: Design, Synthesis, and Applications of “Caged” and Related Photoresponsive Compounds
5. Light activation of transcription: photocaging of nucleotides for control over RNA polymerization
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