Light-induced antibiotic release from a coumarin-caged compound on the ultrafast timescale
Author:
Affiliation:
1. Institute of Physical and Theoretical Chemistry
2. Goethe University Frankfurt
3. 60438 Frankfurt/Main
4. Germany
5. Institute of Organic Chemistry and Chemical Biology
6. Center for Biomolecular Magnetic Resonance (BMRZ)
Abstract
A photocaged puromycin derivative, DEACM-puromycin, was synthesized and characterized. The successful restoration of the antibiotic activity was demonstrated in insect cells.
Funder
Deutsche Forschungsgemeinschaft
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2017/CP/C7CP02030A
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1. Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy
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