Switchable photocatalysis for the chemodivergent benzylation of 4-cyanopyridines-Reference-Cited by-同舟云学术

Switchable photocatalysis for the chemodivergent benzylation of 4-cyanopyridines

Published:2022 Issue:27 Volume:13 Page:8060-8064
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Georgiou Eleni¹²,Spinnato Davide¹²^ORCID,Chen Kang¹,Melchiorre Paolo¹³^ORCID,Muñiz Kilian

Affiliation:

1. ICIQ – Institute of Chemical Research of Catalonia, The Barcelona Institute of Science and Technology, Avenida Països Catalans 16 – 43007, Tarragona, Spain

2. Department of Analytical Chemistry and Organic Chemistry, University Rovira i Virgili (URV), 43007, Tarragona, Spain

3. ICREA, Passeig Lluís Companys 23 – 08010, Barcelona, Spain

Abstract

We report a photocatalytic strategy for the chemodivergent radical benzylation of 4-cyanopyridines. The chemistry uses a single photoredox catalyst to generate benzyl radicals upon N–F bond activation of 2-alkyl N-fluorobenzamides.

Funder

Agencia Estatal de Investigación

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC02698H

Reference34 articles.

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2. Introduction: Photochemical Catalytic Processes

3. Photoredox Catalysis in Organic Chemistry