Visible-light-mediated substituent-controlled regiodivergent (2 + 2)/(3 + 2) cycloadditions for the synthesis of aza-analogs of β-lactam and γ-fused lactam derivatives

Author:

Zuo Wei-Fang1,Zhang Yang1,Luo Yulin1,Li Xiang1ORCID,Zhan Gu1ORCID,Zhou Jin1,Pang Qiwen1ORCID,Yang Qian-Qian1,Han Bo1ORCID

Affiliation:

1. State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China

Abstract

Substituent-controlled regiodivergent synthesis of aza-analogs of β-lactam and γ-fused lactam derivatives via the visible-light-induced Wolff rearrangement of α-diazoketones and azo esters.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Sichuan Province

Publisher

Royal Society of Chemistry (RSC)

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