A honokiol-mediated robust coating for blood-contacting devices with anti-inflammatory, antibacterial and antithrombotic properties

Author:

Li Linhua1ORCID,Chen Chong2,Zhang Chunle1,Luo Rifang3ORCID,Lan Xiaorong3,Guo Fan1,Ma Liang1ORCID,Fu Ping1,Wang Yunbing3ORCID

Affiliation:

1. Kidney Research Institute, National Clinical Research Center for Geriatrics and Division of Nephrology, West China Hospital of Sichuan University, Chengdu 610041, China

2. Laboratory of Biomechanical Engineering, Department of Applied Mechanics, College of Architecture & Environment, Sichuan University, Chengdu, 610064, China

3. National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China

Abstract

A robust and superior honokiol-mediated coating was constructed by a simple, economical and efficient method. The honokiol modified coating possess excellent and long-term anti-inflammatory, anti-infection and anti-thrombotic properties.

Funder

China Postdoctoral Science Foundation

West China Hospital, Sichuan University

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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