An activatable DNA nanodevice for correlated imaging of apoptosis-related dual proteins

Author:

Li Zhixiang12,Feng Xueyan2,Hu Wenping1,Li Lele2ORCID

Affiliation:

1. Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, School of Science, Tianjin 300072, China

2. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China

Abstract

An activated DNA nanodevice was developed for specific imaging of apoptosis-related dual proteins. The aptamer-based sensing function of the system was triggered by the two markers, enabling the imaging of apoptosis in real-time.

Funder

K. C. Wong Education Foundation

Natural Science Foundation of Beijing Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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