Cytochrome c: functions beyond respiration
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm2434.pdf
Reference112 articles.
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4. Liu, X., Kim, C. N., Yang, J., Jemmerson, R. & Wang, X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86, 147–157 (1996). This study stunningly identified cytochrome c as a trigger for caspase activation, thereby hinting at the existence of the mitochondrial pathway of apoptosis.
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