Kinetic model facilitates analysis of fibrin generation and its modulation by clotting factors: implications for hemostasis-enhancing therapies-Reference-Cited by-同舟云学术

Kinetic model facilitates analysis of fibrin generation and its modulation by clotting factors: implications for hemostasis-enhancing therapies

Published:2014 Issue:9 Volume:10 Page:2347-2357
ISSN:1742-206X
Container-title:Mol. BioSyst.
language:en
Short-container-title:Mol. BioSyst.

Author:

Mitrophanov Alexander Y.¹²³⁴,Wolberg Alisa S.⁵⁶⁷,Reifman Jaques¹²³⁴

Affiliation:

1. DoD Biotechnology High Performance Computing Software Applications Institute

2. Telemedicine and Advanced Technology Research Center

3. U.S. Army Medical Research and Materiel Command

4. Ft. Detrick, USA

5. Department of Pathology and Laboratory Medicine

6. University of North Carolina School of Medicine

7. Chapel Hill, USA

Abstract

We developed a computational model that accounts for essential kinetic features of thrombin generation, fibrin formation, and fibrinolysis in diversein vitrosystems. We applied it to characterize strategies to improve hemostasis.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MB/C4MB00263F

Reference73 articles.

1. Fibrinogen and fibrin structure and functions

2. Fibrin Clot Structure and Function

3. Thrombin generation and fibrin clot structure

4. The Dynamics of Thrombin Formation

5. New insights into the molecular mechanisms of the fibrinolytic system

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A Review of Quantitative Systems Pharmacology Models of the Coagulation Cascade: Opportunities for Improved Usability;Pharmaceutics;2023-03-11

2. Family of Asymptotic Solutions to the Two-Dimensional Kinetic Equation with a Nonlocal Cubic Nonlinearity;Symmetry;2022-03-15

3. Thrombin Generation in Trauma Patients: How Do we Navigate Through Scylla and Charybdis?;Current Anesthesiology Reports;2022-01-24

4. In Silico Hemostasis Modeling and Prediction;Hämostaseologie;2020-09-11

5. Injury Length and Arteriole Constriction Shape Clot Growth and Blood-Flow Acceleration in a Mouse Model of Thrombosis;Arteriosclerosis, Thrombosis, and Vascular Biology;2020-09