Hyaluronic acid/poly-l-lysine bilayered silica nanoparticles enhance the osteogenic differentiation of human mesenchymal stem cells
Author:
Affiliation:
1. 3B's Research Group-Biomaterials
2. Biodegradables and Biomimetics
3. University of Minho
4. Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine
5. 4806-909 Taipas, Portugal
Abstract
The coating of silica nanoparticles with a bilayer of poly-l-lysine and hyaluronic acid enhances the osteogenic differentiation of human bone marrow stem cells at low nanoparticle concentrations (25 μg mL−1 and 12.5 μg mL−1).
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2014/TB/C4TB01071J
Reference52 articles.
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3. Unique physical–chemical, apatite-forming properties and human marrow mesenchymal stem cells (HMSCs) response of sol–gel bioactive glass microspheres
4. Internalization of mesoporous silica nanoparticles induces transient but not sufficient osteogenic signals in human mesenchymal stem cells
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